Lighting the way: exploring Blue/Green LED for safe gel documentation

Our Blue/Green LED gel documentation systems: illuminate your research
Our gel documentation systems come with the impressive Blue/Green Transilluminator XL. With twelve powerful LEDs strategically positioned on each side, it guarantees a bright and evenly distributed illumination. The substantial light area, measuring 21x26 cm, facilitates the convenient placement of gels of any size.
 

For half a century, labs relied on UV light and ethidium bromide for DNA visualization, but it's time to break free from this damaging duo. While Blue LEDs emerged as a safer alternative, the efficiency gap compared to Blue/Green LEDs is substantial.

The Blue/Green LED technology is a state-of-the-art solution, operating within a safe light spectrum (470 nm to 520 nm). As a crucial part of our gel documentation systems, Blue/Green LEDs excel at exciting red and green DNA/RNA and fluorescent protein dyes, providing unparalleled intensity and safety. Indeed, since 2014, over 3000 Blue/Green LED devices have been delivering safety and excellence to scientists worldwide.

Untitled picture
The light spectrum of UV light, Blue LED and Blue/Green LED

 

Blue/Green LEDs vs. UV light: a safety showdown

UV light poses risks to both samples and users. The damaging effects on DNA integrity can lead to modifications and degradation, impacting downstream applications such as cloning. Just 30 seconds of UV-light exposure is enough to drastically reduce cloning efficiency! As for the user, exposure to UV light inflicts severe damage on the skin and eyes. The discomfort of wearing protective gear persists throughout usage as viewers must constantly shield their eyes and exposed skin to prevent potential harm. Blue/Green LEDs, on the other hand, emit visible light, preserving DNA integrity and ensuring a safer working environment.

Let's have a closer look at the main differences between Blue/Green LED and UV detection methods:

Blue/Green vs. UV light
Blue/Green vs. UV light

 

Blue/Green LED vs. Blue LED: the broader spectrum application

Except for its safety, the limited excitation range, fluorescent dye compatibility, background interference, intensity constraints, and limited versatility of the Blue LED pose a higher limitation on the gel documentation system, making Blue/Green LEDs a more suitable choice for diverse lab applications.
A more detailed comparison is found in the table below:

BlueGreen vs Blue LED
Blue/Green vs. Blue LED

 

The Blue/Green revolution: efficient, cost-saving, and sustainable technology

In summary, Blue/Green LEDs emit safe visual light (470 nm - 520 nm), ensuring a gel documentation process as safe as reading by a bedside lamp. In contrast, our technology stands as a beacon of safety, preserving DNA integrity and cloning/sequencing efficiency even after prolonged exposure, providing a secure and reliable approach to your molecular biology work. The reassuring safety of Blue/Green LED light does not compromise its exceptional performance, offering superb signals and band intensities, much like the calm and secure ambiance of reading by a well-lit bedside lamp.

  • Safe technology: The LED light is emitted in the visible spectrum and does not cause any damage to the sample or to the user, making it perfect for day-to-day use.
  • Efficient technology:  Blue/Green spectral light efficiently excites red and green DNA/RNA and fluorescently labeled protein dyes through accumulated energy absorption.
  • Cost saving: Stable and reliable, Blue/Green LED lights can be used for up to 20 years of normal laboratory handling. In contrast, UV-light bulbs rapidly lose efficiency and require frequent replacements.

 

Our Blue/Green LED gel documentation systems: illuminate your research
Our gel documentation systems come with the impressive Blue/Green Transilluminator XL. With twelve powerful LEDs strategically positioned on each side, it guarantees a bright and evenly distributed illumination. The substantial light area, measuring 21x26 cm, facilitates the convenient placement of gels of any size.

Unlock the power of innovation with our cutting-edge Blue/Green LED instruments on the market: https://www.nippongenetics.eu/en/product-category/gel-documentation/.

  • FastGene FAS-X: The ultimate stand-alone that requires just 3 simple taps on the touchscreen to get the perfect gel image.
  • FastGene FAS-DIGI PRO: The modular classic of Blue/Green LEDs with full control imaging software.

  • FastGene FAS-DIGI Compact: compact, affordable, and upgradeable.

  • FastGene FAS-BG LED BOX: one imaging system for multiple applications. Use it anywhere at any time.

  • FastGene Blue/Green LED Transilluminator DE: upradeable to full control of gel imaging.


Say goodbye to UV and Blue LEDs and hello to a safer, more powerful alternative!

 

Back to Blog

Related Articles

1000+ Instruments with Blue / Green LEDs

More than 1000 gel doc instruments with Blue/Green LED Technology have been established in the...

FAS-DIGI PRO - The safest way to detect DNA in the Lab

The FAS-DIGI PRO is our high-end gel documentation...

Gel documentation: Safe Blue/Green LED technology on the rise

Convinced laboratories - More than 400 laboratories in Germany and Austria already rely on our ...